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Introduction

Parasitic infections continue to be a global health concern, with millions of people affected each year. One of the major challenges in treating these infections is the emergence of drug resistance in parasites. Understanding the biochemical mechanisms underlying this resistance is crucial for developing more effective therapeutic strategies. This thesis aims to explore the various biochemical mechanisms that parasites employ to resist antiparasitic drugs.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Parasitic Infections
2.2 Drug Resistance in Parasites
2.3 Biochemical Mechanisms of Drug Resistance
2.4 Genetic Basis of Drug Resistance
2.5 Mechanisms of Drug Transport
2.6 Drug Metabolism in Parasites
2.7 Target Site Modifications
2.8 Quorum Sensing in Parasites
2.9 Role of Biofilms in Drug Resistance
2.10 Current Strategies to Combat Drug Resistance

Chapter 3: Research Methodology
3.1 Research Design
3.2 Study Population
3.3 Sampling Techniques
3.4 Data Collection Methods
3.5 Data Analysis Techniques
3.6 Ethical Considerations
3.7 Validation of Research Tools
3.8 Limitations of the Study

Chapter 4: Discussion of Findings
4.1 Overview of Study Findings
4.2 Biochemical Mechanisms of Drug Resistance Identified
4.3 Comparison of Drug Resistance Mechanisms
4.4 Implications of Findings
4.5 Future Research Directions

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Clinical Practice
5.3 Recommendations for Future Research
5.4 Conclusion

Thesis Overview on Biochemical Mechanisms of Drug Resistance in Parasites

Parasitic infections have long been a major public health concern, particularly in developing countries. The emergence of drug resistance in parasites has further complicated the treatment of these infections, leading to increased morbidity and mortality rates. Understanding the biochemical mechanisms that underlie this resistance is essential for developing new and effective treatment strategies.

This thesis aims to provide a comprehensive overview of the biochemical mechanisms of drug resistance in parasites. The literature review will examine the current knowledge on drug resistance in parasites, including the genetic basis of resistance, mechanisms of drug transport, drug metabolism, target site modifications, quorum sensing, and the role of biofilms. The research methodology will outline the study design, population, sampling techniques, data collection methods, and data analysis techniques used in this study.

The findings from this research will be discussed in detail, including the identification of specific biochemical mechanisms of drug resistance in parasites. A comparison of different resistance mechanisms will be provided, along with implications for clinical practice and future research directions. The conclusion will summarize the key findings of the study and provide recommendations for addressing drug resistance in parasites in the future.

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