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**PHD Table of Contents:**

**Chapter 1: Introduction**
– Background of the Study
– Problem Statement
– Research Questions
– Significance of the Study

**Chapter 2: Literature Review**
– History of Antibiotics
– Actinomycetes as Antibiotic Producers
– Biosynthesis of Antibiotics
– Previous Studies on Novel Antibiotics

**Chapter 3: Research Methodology**
– Research Design
– Sampling Method
– Data Collection
– Data Analysis

**Chapter 4: Discussion of Findings**
– Analysis of Data
– Interpretation of Results
– Comparison with Previous Studies

**Chapter 5: Conclusion and Summary**
– Summary of Findings
– Conclusion
– Recommendations for Future Research

**Brief Overview on Biosynthesis of Novel Antibiotics using Actinomycetes:**

The discovery of antibiotics revolutionized the field of medicine, leading to significant advancements in the treatment of infectious diseases. Actinomycetes, a group of filamentous bacteria, have been a major source of antibiotics due to their high metabolic diversity and ability to produce bioactive compounds.

The biosynthesis of antibiotics using actinomycetes involves a complex series of biochemical pathways that lead to the production of novel compounds with potential therapeutic properties. Researchers have been exploring the diversity of actinomycetes in different environments, such as soil and marine habitats, to identify new strains capable of producing unique antibiotics.

This final year project will focus on the biosynthesis of novel antibiotics using actinomycetes, with the aim of isolating and characterizing new strains with potent antibacterial activity. The study will involve the screening of actinomycetes isolates, fermentation of selected strains, extraction of bioactive compounds, and testing of their antimicrobial properties.

By investigating the biosynthetic pathways of novel antibiotics produced by actinomycetes, this research aims to contribute to the development of new antibiotic therapies to combat the increasing threat of antibiotic resistance.

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