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Introduction

Cardiotoxicity is a serious adverse effect of many drugs, leading to significant morbidity and mortality in patients. Drug-induced cardiotoxicity can manifest in various forms, including arrhythmias, myocardial infarction, and heart failure. Understanding the biochemical basis of drug-induced cardiotoxicity is essential for developing strategies to prevent and treat this life-threatening condition.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Mechanisms of drug-induced cardiotoxicity
2.2 Common drugs associated with cardiotoxicity
2.3 Biomarkers for early detection of cardiotoxicity
2.4 Pharmacogenomics of drug-induced cardiotoxicity
2.5 Strategies for prevention and treatment of drug-induced cardiotoxicity
2.6 Animal models for studying drug-induced cardiotoxicity
2.7 Regulatory considerations for cardiotoxicity assessment
2.8 Clinical implications of drug-induced cardiotoxicity
2.9 Emerging trends in the field of drug-induced cardiotoxicity research
2.10 Gaps in current knowledge and future research directions

Chapter 3: Research Methodology
3.1 Study design
3.2 Selection of study population
3.3 Data collection methods
3.4 Biochemical assays for cardiotoxicity assessment
3.5 Statistical analysis
3.6 Ethical considerations
3.7 Quality control measures
3.8 Data interpretation and reporting

Chapter 4: Discussion of Findings
4.1 Overview of study results
4.2 Comparison with existing literature
4.3 Implications for clinical practice
4.4 Strengths and limitations of the study
4.5 Recommendations for future research
4.6 Practical implications of the findings
4.7 Challenges and potential solutions
4.8 Impact on public health

Chapter 5: Conclusion and Summary
In conclusion, drug-induced cardiotoxicity is a complex phenomenon with significant implications for patient safety and public health. By understanding the biochemical basis of this condition and implementing appropriate preventive measures, healthcare providers can minimize the risk of cardiotoxicity in patients receiving potentially harmful medications. This thesis aims to contribute to the existing body of knowledge on drug-induced cardiotoxicity and guide future research efforts in this important area of study.

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