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Introduction

The field of microfluidics has gained significant attention in recent years due to its potential applications in various biomedical fields. Microfluidic devices offer unique capabilities for precise control and manipulation of fluids at the micron scale, making them ideal for a wide range of biomedical applications such as drug delivery, cell sorting, and tissue engineering. This thesis aims to explore the use of microfluidic devices for biomedical applications and investigate their potential impact on healthcare and medicine.

1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter Two: Literature Review
2.1 Overview of Microfluidics
2.2 Applications of Microfluidic Devices in Biomedical Field
2.3 Challenges and Limitations of Microfluidic Devices
2.4 Recent Advances in Microfluidic Technology
2.5 Biomaterials and Microfluidics
2.6 Microfluidic Devices in Drug Delivery
2.7 Microfluidics in Cell Biology
2.8 Microfluidic Devices for Point-of-Care Diagnostics
2.9 Microfluidics in Tissue Engineering
2.10 Future Directions in Microfluidics Research

Chapter Three: System Design and Methodology
3.1 Design Considerations for Microfluidic Devices
3.2 Fabrication Techniques for Microfluidic Devices
3.3 Simulation and Modeling of Microfluidic Systems
3.4 Integration of Microfluidic Devices with Sensors
3.5 Fluid Flow Control in Microfluidic Systems
3.6 Characterization and Testing of Microfluidic Devices
3.7 Optimization of Microfluidic Device Performance
3.8 Biocompatibility and Biofouling Issues in Microfluidics

Chapter Four: System Implementation
4.1 Development of a Microfluidic Device for Drug Delivery
4.2 Implementation of Microfluidic Device for Cell Sorting
4.3 Integration of Microfluidic Devices for Tissue Engineering Applications
4.4 Testing and Validation of Microfluidic Systems
4.5 Scaling Up and Manufacturing of Microfluidic Devices
4.6 Regulatory Considerations for Biomedical Microfluidic Devices
4.7 Clinical Trials and Human Studies with Microfluidic Devices
4.8 Commercialization of Microfluidic Technologies

Chapter Five: Conclusion and Summary
5.1 Summary of Findings
5.2 Contributions to the Field
5.3 Future Directions and Recommendations
5.4 Conclusion

Thesis Overview:
Microfluidic devices have emerged as powerful tools for biomedical applications, offering precise control and manipulation of fluids at the micron scale. This thesis explores the use of microfluidic devices in various biomedical fields such as drug delivery, cell sorting, and tissue engineering. The literature review discusses the current state of microfluidics research, challenges, recent advances, and future directions. The system design and methodology chapter details the design considerations, fabrication techniques, simulation, and integration of microfluidic devices with sensors. The system implementation chapter showcases the development, testing, and validation of microfluidic devices for biomedical applications. The conclusion summarizes the findings, contributions, and provides recommendations for future research in the field. Overall, this thesis aims to contribute to the advancement of microfluidic technologies in biomedical applications for improved healthcare and medicine.

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