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Introduction

Drug resistance has become a significant global health issue that poses a serious threat to the effective treatment of various infectious diseases, including malaria, tuberculosis, and HIV/AIDS. The emergence of drug-resistant strains of pathogens has been attributed to a variety of factors, including the misuse and overuse of antibiotics and antiviral drugs, as well as genetic mutations that confer resistance to drugs. In recent years, there has been a growing recognition of the need to develop innovative strategies to overcome drug resistance and preserve the efficacy of existing and future treatments.

This thesis aims to investigate various strategies for overcoming drug resistance and explore their potential applications in the field of infectious diseases. The research will review the current literature on drug resistance, analyze the challenges posed by resistance mechanisms, and propose novel approaches for combating drug-resistant pathogens. By identifying the key factors contributing to drug resistance and evaluating different strategies to overcome resistance, this study seeks to contribute to the development of more effective and sustainable treatment options.

Table of Contents

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of drug resistance
2.2 Mechanisms of drug resistance
2.3 Factors contributing to drug resistance
2.4 Current challenges in combating drug resistance
2.5 Traditional approaches to overcoming drug resistance
2.6 Novel strategies for combating drug resistance
2.7 Combination therapy and drug resistance
2.8 Drug repurposing and drug resistance
2.9 Technological advances in drug resistance research
2.10 Future directions in the field of drug resistance

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Data analysis techniques
3.4 Sampling strategy
3.5 Ethical considerations
3.6 Research limitations
3.7 Case studies
3.8 Comparative analysis

Chapter 4: Discussion of Findings
4.1 Analysis of research findings
4.2 Comparison of different strategies for overcoming drug resistance
4.3 Implications for practice
4.4 Recommendations for future research
4.5 Integration of findings with existing literature
4.6 Limitations of the study
4.7 Conclusions
4.8 Synthesis of key findings
4.9 Practical implications
4.10 Theoretical implications

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Contributions to the field
5.3 Implications for policy and practice
5.4 Recommendations for further research
5.5 Conclusion

Thesis Overview

Drug resistance has become a major global health challenge, threatening the effectiveness of treatments for various infectious diseases. This thesis explores strategies for overcoming drug resistance in the context of infectious diseases, focusing on innovative approaches to combat resistance mechanisms and enhance treatment outcomes. The study includes a comprehensive review of the current literature on drug resistance, an analysis of different strategies for overcoming resistance, and a discussion of the implications for practice and future research.

Chapter 1 provides an introduction to the topic, outlining the background of the study, the problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. Chapter 2 presents a detailed literature review on drug resistance, including mechanisms, contributing factors, challenges, traditional and novel strategies, combination therapy, drug repurposing, technological advances, and future directions.

Chapter 3 describes the research methodology, including the research design, data collection and analysis methods, sampling strategy, ethical considerations, case studies, and comparative analysis. Chapter 4 offers a thorough discussion of the research findings, analyzing different strategies for overcoming drug resistance, implications for practice, recommendations for future research, limitations, conclusions, and practical and theoretical implications.

Finally, Chapter 5 provides a conclusion and summary of the key findings, contributions to the field, implications for policy and practice, recommendations for further research, and a conclusion. Overall, this thesis aims to advance understanding of drug resistance and provide insights into innovative strategies for overcoming resistance in the treatment of infectious diseases.

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