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Introduction

Déjà vu, a feeling of familiarity or recognition of a present experience as if it has been experienced before, is a common phenomenon experienced by individuals. However, in patients with temporal lobe epilepsy (TLE), déjà vu is often reported as a prodromal symptom or an aura before the onset of a seizure. The neural correlates of déjà vu in TLE have been a topic of interest for researchers in the field of neuroscience, as understanding the underlying mechanisms can provide valuable insights into the pathophysiology of TLE.

Background of Study

Temporal lobe epilepsy is a neurological disorder characterized by recurrent seizures originating from the temporal lobes of the brain. Déjà vu has long been associated with TLE, with studies suggesting that aberrant neural activity in the temporal lobes may play a role in the experience of déjà vu in these patients. However, the exact neural mechanisms underlying déjà vu in TLE remain poorly understood.

Problem Statement

The neural correlates of déjà vu in TLE have not been thoroughly investigated, and there is a lack of consensus in the literature regarding the underlying mechanisms. Understanding the neural basis of déjà vu in TLE is crucial for developing more effective diagnostic and treatment strategies for patients with this condition.

Objective of Study

The main objective of this study is to investigate the neural correlates of déjà vu in patients with TLE. Specifically, we aim to identify the brain regions and neural pathways involved in the experience of déjà vu in these patients.

Limitation of Study

Due to the complex nature of epilepsy and the subjective nature of déjà vu experiences, there are several limitations to this study. These include the small sample size of patients, the variability in déjà vu experiences across individuals, and the challenges in accurately measuring neural activity in the temporal lobes.

Scope of Study

This study will focus on patients with TLE who experience déjà vu as a prodromal symptom or aura before seizures. We will use neuroimaging techniques such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) to investigate the neural correlates of déjà vu in these patients.

Significance of Study

Understanding the neural correlates of déjà vu in TLE can provide valuable insights into the underlying mechanisms of this phenomenon and may lead to the development of novel diagnostic and treatment approaches for patients with TLE.

Structure of the Thesis

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of Temporal Lobe Epilepsy
2.2 Déjà vu in Temporal Lobe Epilepsy
2.3 Neural Correlates of Déjà vu
2.4 Neuroimaging Studies in Temporal Lobe Epilepsy
2.5 Seizure Prediction and Prevention
2.6 Treatment Approaches for Temporal Lobe Epilepsy
2.7 Cognitive and Emotional Aspects of Déjà vu
2.8 Theoretical Models of Memory and Recognition
2.9 Impact of Déjà vu on Quality of Life
2.10 Gaps in the Literature

Chapter 3: Research Methodology
3.1 Study Design
3.2 Participants
3.3 Data Collection Procedures
3.4 Neuroimaging Techniques
3.5 Data Analysis Methods
3.6 Ethical Considerations
3.7 Validity and Reliability
3.8 Limitations of Methodology

Chapter 4: Discussion of Findings
4.1 Neural Correlates of Déjà vu in TLE
4.2 Brain Regions and Neural Pathways Involved
4.3 Implications for Diagnosis and Treatment
4.4 Future Research Directions
4.5 Comparison with Existing Literature

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Clinical Practice
5.3 Limitations of the Study
5.4 Recommendations for Future Research
5.5 Conclusion

Thesis Overview on Neural Correlates of Déjà vu in Temporal Lobe Epilepsy

Déjà vu is a common phenomenon experienced by individuals, but in patients with temporal lobe epilepsy (TLE), it is often reported as a prodromal symptom or an aura before seizures. The neural correlates of déjà vu in TLE have been a topic of interest for researchers, as understanding the underlying mechanisms can provide insights into the pathophysiology of the disorder.

This thesis aims to investigate the neural correlates of déjà vu in patients with TLE. Chapter 1 provides an introduction to the study, outlining the background, problem statement, objectives, limitations, scope, significance, and structure of the thesis. Chapter 2 presents a comprehensive literature review on TLE, déjà vu, neural correlates, neuroimaging studies, seizure prediction, treatment approaches, theoretical models, and the impact of déjà vu on quality of life.

Chapter 3 details the research methodology, including the study design, participants, data collection procedures, neuroimaging techniques, data analysis methods, ethical considerations, and limitations. Chapter 4 discusses the findings of the study, focusing on the neural correlates of déjà vu in TLE, brain regions and neural pathways involved, implications for diagnosis and treatment, future research directions, and a comparison with existing literature.

Chapter 5 provides a conclusion and summary of the project, summarizing the findings, discussing implications for clinical practice, addressing limitations of the study, making recommendations for future research, and concluding the thesis. This study aims to contribute to the understanding of the neural basis of déjà vu in TLE and may have implications for the diagnosis and treatment of patients with this condition.

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