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Introduction

Post-traumatic stress disorder (PTSD) is a psychological condition that develops in individuals who have experienced a traumatic event such as warfare, natural disasters, or interpersonal violence. While the symptoms of PTSD can vary widely, they often include intrusive memories, avoidance of reminders of the trauma, negative changes in mood and cognition, and hyperarousal. The neurobiological mechanisms underlying PTSD are complex and not yet fully understood, making it a challenging condition to treat effectively.

This thesis will explore the neurobiological mechanisms of PTSD and examine current treatment options for the disorder. By understanding how PTSD affects the brain and body, we can develop more targeted and effective interventions for those suffering from this debilitating condition.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of PTSD
2.2 Neurobiological basis of PTSD
2.3 Genetic factors in PTSD
2.4 Neuroimaging studies of PTSD
2.5 Neuroendocrine dysregulation in PTSD
2.6 Neurotransmitter abnormalities in PTSD
2.7 Cognitive and emotional processing in PTSD
2.8 Current treatment approaches for PTSD
2.9 Pharmacological interventions for PTSD
2.10 Psychotherapeutic interventions for PTSD

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Measures
3.4 Data collection procedures
3.5 Data analysis
3.6 Ethical considerations
3.7 Limitations of the study
3.8 Conclusion

Chapter 4: Discussion of Findings
4.1 Neurobiological mechanisms of PTSD
4.2 Treatment efficacy for PTSD
4.3 Implications for clinical practice
4.4 Future research directions
4.5 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Implications for practice
5.3 Limitations of the study
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview

Post-traumatic stress disorder (PTSD) is a debilitating condition that affects individuals who have experienced traumatic events. The neurobiological mechanisms underlying PTSD are complex, involving changes in brain structure and function, neuroendocrine dysregulation, and alterations in neurotransmitter systems. Understanding these mechanisms is crucial for developing effective treatment strategies for PTSD.

This thesis will review the current literature on the neurobiological mechanisms of PTSD, including genetic factors, neuroimaging studies, and neuroendocrine dysregulation. It will also discuss current treatment approaches for PTSD, including pharmacological and psychotherapeutic interventions. By synthesizing this information, we can gain a better understanding of how PTSD affects the brain and body, and improve treatment outcomes for individuals with this disorder.

Through a comprehensive literature review, research methodology, and discussion of findings, this thesis aims to contribute to the growing body of knowledge on PTSD and its treatment. By shedding light on the neurobiological basis of PTSD, we can develop more targeted and effective interventions for those suffering from this debilitating condition.

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