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Introduction

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. Despite advancements in diagnosis and treatment, cancer remains a leading cause of mortality worldwide. MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in the regulation of gene expression. Dysregulation of miRNAs has been linked to various diseases, including cancer.

The role of miRNAs in cancer development has gained significant attention in recent years. Studies have shown that miRNAs can act as oncogenes or tumor suppressors, depending on the target genes they regulate. Understanding the role of miRNAs in cancer development could lead to the development of novel diagnostic and therapeutic strategies for this deadly disease.

This thesis aims to explore the role of miRNAs in cancer development. The following chapters will provide a comprehensive overview of the background of the study, the problem statement, objectives, limitations, scope, significance of the study, and the structure of the thesis. Additionally, key terms relevant to the topic will be defined.

Table of Contents

Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of miRNAs
2.2 Role of miRNAs in cancer development
2.3 Oncogenic miRNAs
2.4 Tumor suppressor miRNAs
2.5 Dysregulated miRNAs in different types of cancer
2.6 Diagnostic and therapeutic implications of miRNAs in cancer
2.7 Current challenges and future directions in miRNA research
2.8 miRNA-based therapies in clinical trials
2.9 miRNAs as potential biomarkers for cancer prognosis
2.10 Role of miRNAs in cancer metastasis

Chapter 3: Research Methodology
3.1 Study design
3.2 Selection of study participants
3.3 Data collection methods
3.4 Data analysis techniques
3.5 Validation of miRNA targets
3.6 In vitro and in vivo experiments
3.7 Bioinformatic analysis of miRNA-mRNA interactions
3.8 Statistical analysis

Chapter 4: Discussion of Findings
4.1 Overview of research findings
4.2 Role of specific miRNAs in cancer development
4.3 Mechanisms of miRNA dysregulation in cancer
4.4 Functional validation of miRNA targets
4.5 Implications for cancer diagnosis and therapy
4.6 Future directions in miRNA research

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Conclusions drawn from the study
5.3 Recommendations for future research
5.4 Implications for cancer treatment and management

This thesis will provide valuable insights into the role of miRNAs in cancer development, with potential implications for cancer diagnosis, prognosis, and therapy.

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