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Introduction

Body-focused repetitive behavior disorders (BFRBs) are a group of psychological disorders characterized by repetitive self-grooming behaviors that result in damage to the body. Examples of BFRBs include trichotillomania (hair-pulling disorder), excoriation (skin-picking) disorder, and onychophagia (nail-biting). Despite the significant impact these disorders can have on individuals’ physical and emotional well-being, there is still much that is unknown about their underlying mechanisms and optimal treatment strategies.

Novel targets in BFRBs hold great promise for advancing our understanding of these disorders and improving treatment outcomes. By identifying new targets within the brain and body that contribute to the development and maintenance of BFRBs, researchers can develop more targeted and effective interventions. This thesis aims to explore the current state of knowledge on novel targets in BFRBs and their potential implications for future research and clinical practice.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of BFRBs
2.2 Current treatment approaches for BFRBs
2.3 Neurobiological mechanisms of BFRBs
2.4 Psychosocial factors contributing to BFRBs
2.5 Comorbidity of BFRBs with other mental health disorders
2.6 Role of genetics in BFRBs
2.7 Neuroimaging studies on BFRBs
2.8 Emerging research on novel targets in BFRBs
2.9 Summary of key findings
2.10 Gaps in the literature and research needs

Chapter 3: Research Methodology
3.1 Research design
3.2 Participant recruitment and selection
3.3 Data collection methods
3.4 Data analysis procedures
3.5 Ethical considerations
3.6 Recruitment challenges and strategies
3.7 Data management and storage
3.8 Quality assurance measures
3.9 Limitations of the methodology

Chapter 4: Discussion of Findings
4.1 Overview of study findings
4.2 Comparison with existing literature
4.3 Implications for clinical practice
4.4 Recommendations for future research
4.5 Strengths and limitations of the study
4.6 Theoretical and practical implications
4.7 Conclusion

Chapter 5: Conclusion
5.1 Summary of key findings
5.2 Contributions to the field
5.3 Practical implications for clinicians
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview: Novel targets in body-focused repetitive behavior disorders

Body-focused repetitive behavior disorders (BFRBs) are a group of psychiatric conditions characterized by repetitive grooming behaviors that result in physical harm. Despite the prevalence and impact of BFRBs, there is still much to be understood about their underlying mechanisms and optimal treatment strategies. This thesis aims to explore novel targets in BFRBs, focusing on identifying new areas within the brain and body that contribute to the development and maintenance of these disorders.

Chapter 1 provides an introduction to BFRBs, including background information, the problem statement, objectives of the study, limitations, scope, significance, and definitions of key terms. Chapter 2 presents a comprehensive literature review on BFRBs, covering current treatment approaches, neurobiological mechanisms, psychosocial factors, genetics, neuroimaging studies, and emerging research on novel targets.

Chapter 3 details the research methodology used in this study, including research design, participant selection, data collection and analysis, ethical considerations, recruitment challenges, data management, and quality assurance. Chapter 4 discusses the findings of the study, comparing them with existing literature, exploring implications for clinical practice, recommending future research directions, and highlighting the strengths and limitations of the study.

Chapter 5 concludes the thesis with a summary of key findings, contributions to the field, practical implications for clinicians, recommendations for future research, and a final conclusion. The research conducted in this thesis aims to advance our understanding of BFRBs and offer new insights into potential targets for intervention and treatment in individuals with these disorders.

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