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Introduction

Neuromodulation is a rapidly evolving field in neuroscience that involves the use of various techniques to regulate or alter the activity of the nervous system. Post-stroke depression is a common and debilitating complication that affects a significant portion of stroke survivors. While traditional treatment methods such as medication and therapy have shown some efficacy, there is a growing interest in the use of neuromodulation techniques as a potential alternative or adjunctive therapy for post-stroke depression.

This thesis aims to explore the potential of neuromodulation as a treatment option for post-stroke depression. Specifically, the focus will be on the use of non-invasive neuromodulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). These techniques have shown promise in treating various psychiatric conditions and are relatively safe and well-tolerated, making them attractive options for stroke survivors who may be more vulnerable to the side effects of traditional medications.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Prevalence of post-stroke depression
2.2 Etiology of post-stroke depression
2.3 Current treatment options for post-stroke depression
2.4 Neuromodulation techniques
2.5 Evidence for the efficacy of neuromodulation in psychiatric disorders
2.6 Studies on neuromodulation for post-stroke depression
2.7 Mechanisms of action of neuromodulation
2.8 Safety and tolerability of neuromodulation techniques
2.9 Individual differences in response to neuromodulation
2.10 Future directions and challenges in the use of neuromodulation for post-stroke depression

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Procedures
3.4 Neuromodulation protocols
3.5 Outcome measures
3.6 Data analysis
3.7 Ethical considerations
3.8 Timeline

Chapter 4: Discussion of Findings
4.1 Participant characteristics
4.2 Effects of neuromodulation on depressive symptoms
4.3 Effects of neuromodulation on functional outcomes
4.4 Comparison with traditional treatment methods
4.5 Adverse effects and tolerability
4.6 Mechanisms underlying the effects of neuromodulation
4.7 Individual differences in response to neuromodulation
4.8 Implications for clinical practice
4.9 Limitations of the study
4.10 Future research directions

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Implications for practice
5.3 Contributions to the field
5.4 Strengths and limitations of the study
5.5 Recommendations for future research
5.6 Conclusion

Thesis Overview:

Neuromodulation has emerged as a promising treatment option for post-stroke depression, a common and debilitating complication affecting stroke survivors. This thesis aims to explore the potential of non-invasive neuromodulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) in alleviating depressive symptoms and improving functional outcomes in stroke survivors.

The literature review will provide a comprehensive overview of the prevalence and etiology of post-stroke depression, current treatment options, and the evidence supporting the use of neuromodulation in psychiatric disorders. The research methodology section will outline the study design, participant recruitment, neuromodulation protocols, outcome measures, data analysis procedures, and ethical considerations.

The discussion of findings will present the results of the study, including the effects of neuromodulation on depressive symptoms and functional outcomes, comparisons with traditional treatment methods, adverse effects, mechanisms of action, individual differences in response, and implications for clinical practice. The conclusion and summary will summarize the findings, discuss their implications, highlight the contributions of the study, identify strengths and limitations, provide recommendations for future research, and conclude the thesis.

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