Drug repurposing for oral diseases – Complete Phd and Masters Thesis

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Introduction

Drug repurposing, also known as drug repositioning, is the process of identifying new therapeutic uses for existing drugs that are outside the scope of the original medical indication. This approach offers significant advantages in the field of drug discovery and development, as it leverages existing safety and pharmacokinetic profiles of drugs to potentially expedite the clinical development process. Oral diseases, encompassing a wide range of conditions affecting the oral cavity and surrounding structures, represent a significant global health burden. Despite advancements in oral healthcare, there remains a need for novel and effective treatment strategies for oral diseases. Drug repurposing holds promise in addressing this unmet medical need by identifying existing drugs that may have therapeutic potential in the management of oral diseases.

Table of Contents

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of oral diseases
2.2 Drug repurposing in healthcare
2.3 Drug repurposing in oral healthcare
2.4 Existing drugs with potential for repurposing in oral diseases
2.5 Challenges and opportunities in drug repurposing for oral diseases
2.6 Regulatory considerations in drug repurposing
2.7 Case studies of successful drug repurposing in oral diseases
2.8 Future directions in drug repurposing for oral diseases

Chapter 3: Research Methodology
3.1 Research design
3.2 Study population
3.3 Data collection methods
3.4 Data analysis
3.5 Ethical considerations
3.6 Validity and reliability of findings
3.7 Limitations of the study
3.8 Future research directions

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Comparison of repurposed drugs in oral diseases
4.3 Mechanisms of action of repurposed drugs
4.4 Safety and efficacy of repurposed drugs
4.5 Challenges and limitations of repurposed drugs
4.6 Implications for clinical practice
4.7 Recommendations for further research

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Conclusions drawn from the study
5.3 Implications for healthcare practice
5.4 Recommendations for policy and clinical guidelines
5.5 Contribution to the field of drug repurposing for oral diseases
5.6 Suggestions for future research avenues

Thesis Overview on Drug Repurposing for Oral Diseases

Oral diseases pose a significant public health challenge globally, affecting individuals of all ages and socioeconomic backgrounds. The traditional approach to drug discovery and development is lengthy, costly, and often unsuccessful, leading to a pressing need for innovative strategies to identify effective treatments for oral diseases. Drug repurposing offers a promising avenue for addressing this need by repurposing existing drugs for new therapeutic indications in oral healthcare.

The thesis on drug repurposing for oral diseases aims to explore the potential of drug repurposing in addressing unmet medical needs in oral healthcare. The literature review will provide an overview of oral diseases, drug repurposing in healthcare, and specific examples of drugs with potential for repurposing in oral diseases. The research methodology will outline the study design, data collection methods, and analysis techniques used to investigate the efficacy and safety of repurposed drugs in oral diseases.

The discussion of findings will encompass a comparative analysis of repurposed drugs in oral diseases, mechanisms of action, safety and efficacy profiles, and implications for clinical practice. The conclusion and summary will summarize key findings, draw conclusions from the study, provide recommendations for policy and clinical guidelines, and suggest future research directions in the field of drug repurposing for oral diseases.

Overall, this thesis aims to contribute to the growing body of literature on drug repurposing in oral healthcare and provide valuable insights into the potential of repurposed drugs in improving outcomes for patients with oral diseases.

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