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Introduction

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social interaction and communication, as well as restricted and repetitive behaviors. While the exact cause of ASD remains unknown, there is growing evidence to suggest that neuroinflammation may play a significant role in the pathogenesis of the disorder. Neuroinflammation is characterized by activation of the brain’s immune response, leading to the release of pro-inflammatory molecules that can disrupt normal brain development and function. Understanding the role of neuroinflammation in ASD is crucial for developing effective treatments and interventions for individuals with the disorder.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Autism Spectrum Disorder
2.2 Neuroinflammation in ASD
2.3 The Immune System and the Brain
2.4 Neuroinflammatory Markers in ASD
2.5 Animal Models of Neuroinflammation in ASD
2.6 Neuroinflammation and Behavioral Changes in ASD
2.7 Genetic and Environmental Factors in Neuroinflammation
2.8 Neuroinflammation and Neuroimaging in ASD
2.9 Therapeutic Approaches Targeting Neuroinflammation
2.10 Gaps in the Literature

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Measurements and Instruments
3.4 Data Collection Procedures
3.5 Data Analysis
3.6 Ethical Considerations
3.7 Limitations of the Methodology
3.8 Future Directions

Chapter 4: Discussion of Findings
4.1 Neuroinflammatory Markers in ASD
4.2 Genetic and Environmental Factors in Neuroinflammation
4.3 Therapeutic Approaches Targeting Neuroinflammation
4.4 Neuroinflammation and Neuroimaging in ASD
4.5 Behavioral Changes in ASD
4.6 Implications for Diagnosis and Treatment
4.7 Limitations of the Study
4.8 Future Research Directions

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Clinical Practice
5.3 Strengths and Limitations of the Study
5.4 Recommendations for Future Research

Thesis Overview:

Neuroinflammation in autism spectrum disorders is a topic of growing interest in the field of autism research. This thesis aims to provide a comprehensive overview of the current understanding of neuroinflammation in ASD, including its potential role in the pathogenesis of the disorder, neuroinflammatory markers, genetic and environmental factors influencing neuroinflammation, and therapeutic approaches targeting neuroinflammation. By reviewing the existing literature, discussing research methodologies, presenting findings, and offering conclusions and recommendations for future research, this thesis seeks to contribute to the growing body of knowledge on neuroinflammation in ASD and its implications for diagnosis and treatment.

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