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Introduction:

Parkinsonʼs disease (PD) is a neurodegenerative disorder that primarily affects movement, but also has cognitive and memory impairments. Prospective memory refers to the ability to remember to carry out intentions in the future, such as remembering to take medication at a specific time. Neuroimaging techniques, such as structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET), have provided valuable insights into the neural mechanisms underlying prospective memory in healthy individuals. However, there is limited research on the neuroimaging of prospective memory in individuals with PD. Understanding the neural correlates of prospective memory in PD may provide important insights into the cognitive deficits associated with the disease and may aid in the development of more effective interventions.

Table of Contents:

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of Parkinsonʼs disease
2.2 Cognitive deficits in Parkinsonʼs disease
2.3 Prospective memory in healthy individuals
2.4 Neuroimaging techniques in cognitive neuroscience
2.5 Neuroimaging studies of memory in Parkinsonʼs disease
2.6 Neural correlates of prospective memory
2.7 Prospective memory deficits in Parkinsonʼs disease
2.8 Neuroimaging of prospective memory in Parkinsonʼs disease
2.9 Gaps in the current literature
2.10 Summary of key findings

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Neuroimaging protocols
3.4 Prospective memory task
3.5 Data analysis
3.6 Ethical considerations
3.7 Pilot study
3.8 Limitations and challenges
3.9 Conclusion

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Neural correlates of prospective memory in Parkinsonʼs disease
4.3 Comparison with healthy individuals
4.4 Implications for clinical practice
4.5 Future research directions
4.6 Strengths and limitations
4.7 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Implications for theory and practice
5.3 Contributions to the field
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview:

Neuroimaging of prospective memory in Parkinsonʼs disease is a research project that aims to investigate the neural correlates of prospective memory deficits in individuals with PD using advanced neuroimaging techniques. The thesis will begin with an introduction that provides background information on PD and prospective memory, as well as the rationale for the study. This will be followed by a comprehensive literature review that examines existing research on cognitive deficits in PD, prospective memory in healthy individuals, and neuroimaging studies of memory. The research methodology chapter will outline the study design, participant selection process, neuroimaging protocols, prospective memory task, data analysis procedures, and ethical considerations.

The discussion of findings chapter will present and interpret the results of the study, highlighting the neural correlates of prospective memory deficits in PD and comparing them with findings in healthy individuals. The conclusion and summary chapter will provide a summary of the key findings, discuss their implications for theory and practice, outline contributions to the field, suggest directions for future research, and conclude the thesis. Overall, this thesis will contribute to the growing body of knowledge on cognitive deficits in PD and advance our understanding of the neural mechanisms underlying prospective memory.

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