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**Introduction**

Capillary electrophoresis (CE) is a powerful analytical technique that has gained popularity in various fields, including toxicology screening. The ability of CE to separate and quantify a wide range of analytes with high efficiency and sensitivity makes it an attractive method for detecting and quantifying toxic substances in biological samples. The aim of this thesis is to evaluate different CE methods for toxicology screening, with a focus on their applicability, performance, and limitations.

**Table of Contents**

**Chapter 1: Introduction**
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

**Chapter 2: Literature Review**
– Overview of capillary electrophoresis
– Applications of capillary electrophoresis in toxicology screening
– Comparison of capillary electrophoresis with other analytical techniques
– Importance of method validation in toxicology screening
– Current trends and developments in capillary electrophoresis for toxicology screening
– Challenges and limitations of capillary electrophoresis in toxicology screening
– Case studies using capillary electrophoresis for toxicology screening
– Future prospects of capillary electrophoresis in toxicology screening

**Chapter 3: Research Methodology**
– Selection of CE methods for evaluation
– Sample preparation techniques
– Instrumentation and conditions
– Method validation parameters
– Data analysis and interpretation
– Quality control measures
– Experimental design
– Statistical analysis

**Chapter 4: Discussion of Findings**
– Comparison of CE methods for toxicology screening
– Evaluation of method performance
– Identification of limitations and challenges
– Recommendations for improvement
– Interpretation of results
– Implications for toxicology screening
– Comparison with existing literature

**Chapter 5: Conclusion and Summary**
– Summary of key findings
– Contribution to the field of toxicology screening
– Recommendations for future research
– Conclusion

**Thesis Overview**

The field of toxicology screening plays a crucial role in public health and safety by detecting and quantifying toxic substances in various biological samples. Capillary electrophoresis (CE) has emerged as a valuable analytical tool for toxicology screening due to its high separation efficiency, sensitivity, and versatility. This thesis aims to evaluate different CE methods for toxicology screening, with a focus on their performance, applicability, and limitations.

In Chapter 1, the introduction provides background information on CE and its relevance in toxicology screening. The problem statement highlights the need for evaluating CE methods for toxicology screening, while the objectives outline the goals of the study. The scope and limitations of the research are also discussed, along with the significance of the study. The structure of the thesis and key definitions are provided to guide the reader through the content.

Chapter 2 includes a comprehensive literature review on CE in toxicology screening, covering its applications, comparison with other techniques, method validation, current trends, challenges, case studies, and future prospects. This review sets the stage for the research methodology outlined in Chapter 3, which details the selection of CE methods, sample preparation, instrumentation, validation parameters, data analysis, experimental design, and statistical analysis.

In Chapter 4, the findings of the study are discussed in depth, including comparisons of CE methods, evaluation of method performance, identification of limitations, recommendations for improvement, and implications for toxicology screening. The results are interpreted in light of existing literature to provide a comprehensive understanding of the topic.

Finally, Chapter 5 presents the conclusion and summary of the thesis, summarizing key findings, contributions to the field, recommendations for future research, and a final conclusion. This thesis aims to contribute to the advancement of CE methods for toxicology screening and provide valuable insights for researchers and practitioners in the field.

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