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Introduction

Cancer is a leading cause of death worldwide, with millions of individuals diagnosed each year. Despite advancements in treatments, many cancer patients still face poor outcomes due to resistance to conventional therapies. MicroRNAs (miRNAs) have emerged as promising therapeutic targets for cancer treatment due to their ability to regulate gene expression and influence various biological processes. In this thesis, we will explore the potential of miRNA-based therapeutic strategies in the treatment of cancer.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of cancer
2.2 Role of microRNAs in cancer
2.3 Current treatment strategies for cancer
2.4 MicroRNA-based therapeutic approaches
2.5 Clinical trials using miRNA-based therapies
2.6 Challenges and limitations of miRNA therapy
2.7 Combination therapies with miRNAs
2.8 Biomarkers for miRNA-based therapies
2.9 Delivery systems for miRNA therapeutics
2.10 Future directions in miRNA-based cancer therapy

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Sample population
3.4 In vitro and in vivo experiments
3.5 miRNA screening and selection
3.6 Data analysis techniques
3.7 Statistical analysis
3.8 Ethical considerations

Chapter 4: Discussion of Findings
4.1 Analysis of miRNA expression profiles
4.2 Efficacy of miRNA-based therapies
4.3 Mechanisms of action of miRNAs in cancer
4.4 Comparison with conventional therapies
4.5 Adverse effects and toxicity of miRNA therapies
4.6 Personalized medicine approaches
4.7 Overcoming resistance to miRNA therapy
4.8 Future implications of miRNA-based cancer therapy

Chapter 5: Conclusion and Summary
In this final chapter, we will summarize the key findings of the thesis and discuss the implications for the future of miRNA-based therapeutic strategies in cancer treatment. We will also provide recommendations for further research in this field.

Thesis Overview

This thesis aims to explore the potential of miRNA-based therapeutic strategies in the treatment of cancer. Chapter 1 provides an introduction to the topic, including the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of terms.

Chapter 2 consists of a comprehensive literature review on the role of miRNAs in cancer, current treatment strategies, miRNA-based therapeutic approaches, clinical trials, challenges, combination therapies, biomarkers, delivery systems, and future directions.

Chapter 3 details the research methodology, including research design, data collection methods, sample population, experiments, miRNA screening, data analysis, statistical analysis, and ethical considerations.

Chapter 4 presents a discussion of findings, analyzing miRNA expression profiles, efficacy of therapies, mechanisms of action, comparison with conventional treatments, adverse effects, personalized medicine, resistance, and future implications.

Chapter 5 concludes the thesis, summarizing key findings and discussing the implications for miRNA-based cancer therapy, as well as offering recommendations for future research. Overall, this thesis aims to contribute to the growing body of knowledge on miRNA-based therapeutic strategies in cancer and provide insights for the development of novel treatment approaches in the future.

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