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Introduction:

Epigenetic modifications play a crucial role in regulating gene expression and have been implicated in various biological processes, including the development of drug resistance in cancer cells. Understanding how epigenetic changes contribute to drug resistance is essential for the development of more effective treatment strategies. This thesis aims to explore the role of epigenetic modifications in the development of drug resistance, focusing on their impact on cancer cells.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of epigenetics
2.2 Epigenetic modifications and cancer
2.3 Drug resistance in cancer
2.4 Role of epigenetic modifications in drug resistance
2.5 Mechanisms of epigenetic regulation
2.6 Current treatment strategies for drug-resistant cancers
2.7 Targeting epigenetic modifications for overcoming drug resistance
2.8 Clinical implications of epigenetic therapies
2.9 Emerging trends in epigenetic research
2.10 Gaps in current knowledge

Chapter 3: Research Methodology
3.1 Research design
3.2 Study population
3.3 Data collection methods
3.4 Data analysis techniques
3.5 Ethical considerations
3.6 Sample size calculation
3.7 Research instruments
3.8 Data validation techniques

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Analysis of results
4.3 Comparison with existing literature
4.4 Implications for clinical practice
4.5 Recommendations for future research
4.6 Strengths and limitations of the study

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Contributions to the field
5.3 Practical implications
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview on Exploring the Role of Epigenetic Modifications in the Development of Drug Resistance:

Epigenetic modifications have emerged as important regulators of gene expression in various biological processes, including the development of drug resistance in cancer cells. This thesis aims to provide a comprehensive overview of the role of epigenetic modifications in drug resistance, focusing on their impact on cancer cells. The literature review will explore the current understanding of epigenetic mechanisms in drug resistance and highlight gaps in knowledge that require further investigation. The research methodology section will outline the study design, data collection methods, and analysis techniques used to investigate the role of epigenetic modifications in drug resistance. The discussion of findings will present the results of the study and their implications for clinical practice, while the conclusion and summary chapter will summarize key findings and offer recommendations for future research in this important area of study.

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