[ad_1] Introduction Drug-drug interactions (DDIs) have been recognized as a significant concern in healthcare, as they can lead to adverse effects, decreased therapeutic efficacy, and even treatment failure. Transporters, particularly membrane transport proteins such as…
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[ad_1] **Introduction** Diabetes is a chronic metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It is a major public health concern worldwide, with an estimated 422 million adults…
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[ad_1] Introduction: The intricate connection between the gut and the brain has garnered increasing attention in recent years, with emerging evidence suggesting that the gut-brain axis plays a crucial role in various physiological processes, including…
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[ad_1] Introduction The blood-brain barrier (BBB) is a highly selective semipermeable membrane that separates the circulating blood from the brain extracellular fluid in order to protect the brain from potentially harmful substances. However, this barrier…
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[ad_1] Introduction Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system and plays a crucial role in the regulation of neuronal excitability. Drugs that target the GABAergic system have been…
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[ad_1] Introduction The field of drug discovery and development has continuously evolved over the years, with researchers constantly exploring new strategies to target various biological processes. One such area of interest is the development of…
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[ad_1] Introduction Hypertension, also known as high blood pressure, is a common chronic condition that affects millions of people worldwide. It is a major risk factor for cardiovascular diseases, stroke, and kidney failure. Pharmacological management…
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[ad_1] Introduction: Evaluation of drug-induced QT prolongation is a crucial aspect of pharmacovigilance as it is associated with an increased risk of life-threatening cardiac arrhythmias, such as Torsades de Pointes. QT prolongation occurs when the…
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[ad_1] Introduction Inflammation is a natural response by the body to injury or infection, but if left unchecked, it can lead to chronic inflammatory conditions such as arthritis, asthma, and inflammatory bowel disease. Anti-inflammatory drugs…
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[ad_1] Introduction: Stem cells have gained significant interest in the field of regenerative medicine due to their unique ability to differentiate into various cell types and repair damaged tissues. These multipotent cells hold great promise…
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