[ad_1] Introduction Ototoxicity refers to the toxic effects of drugs on the auditory system, leading to hearing loss, tinnitus, or imbalance. It is a common side effect of many medications, including antibiotics, chemotherapy drugs, and…
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[ad_1] Introduction Drug-binding proteins play a crucial role in pharmacokinetics by affecting the distribution, metabolism, and excretion of drugs in the body. These proteins, such as albumin and alpha-1 acid glycoprotein, bind to drugs and…
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[ad_1] Introduction Pharmacogenomics is an emerging field that combines pharmacology and genomics to personalize drug therapy based on an individual’s genetic makeup. Antiepileptic drugs (AEDs) are commonly used to treat epilepsy, a neurological disorder characterized…
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[ad_1] Introduction The gut microbiome plays a crucial role in the metabolism of drugs, which can have significant implications for drug efficacy, toxicity, and personalized medicine. Understanding the interactions between drugs and the gut microbiome…
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[ad_1] Introduction Chronic kidney disease (CKD) is a significant public health issue affecting millions of people worldwide. One of the major complications of CKD is the impact it has on drug clearance and metabolism, leading…
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[ad_1] Introduction: Pharmacokinetics is a key aspect of drug development that focuses on the absorption, distribution, metabolism, and excretion of drugs within the body. Prodrugs are inactive chemical derivatives of drugs that are converted into…
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[ad_1] Introduction Evaluation of drug-induced cardiotoxicity is an important area of research in the field of pharmacology and cardiology. Cardiotoxicity refers to the detrimental effects of drugs on the heart, leading to various cardiac dysfunctions…
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[ad_1] Introduction Cancer remains one of the leading causes of death worldwide, with chemotherapy being one of the most common treatment modalities. However, one of the major challenges in the successful treatment of cancer is…
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[ad_1] Introduction Opioid analgesics are commonly used for pain management in clinical settings due to their potent analgesic effects. However, the pharmacodynamics of these drugs are complex and poorly understood. This thesis aims to provide…
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[ad_1] Introduction Pharmacogenomics is a field of study that investigates how an individual’s genetic makeup influences their response to medications. In the case of antidepressants, the field of pharmacogenomics has gained significant attention in recent…
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