Novel targets for Alzheimerʼs disease therapy – Complete Phd and Masters Thesis

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Introduction

Alzheimer’s disease is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Despite decades of research, there is still no cure for this devastating disease, and current treatment options are limited in their effectiveness. In recent years, there has been increasing interest in exploring novel targets for Alzheimer’s disease therapy, with the hope of developing more effective treatments that can slow or even reverse the progression of the disease.

This thesis aims to investigate novel targets for Alzheimer’s disease therapy, with a focus on identifying potential new pathways and molecules that could be targeted to treat this condition. By exploring new avenues for treatment, it is hoped that this research will contribute to the development of more effective therapies for Alzheimer’s disease, ultimately improving the quality of life for patients and their families.

Table of Contents

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of Alzheimer’s disease
2.2 Current treatment options
2.3 Pathophysiology of Alzheimer’s disease
2.4 Role of amyloid-beta in Alzheimer’s disease
2.5 Role of tau protein in Alzheimer’s disease
2.6 Inflammation and Alzheimer’s disease
2.7 Oxidative stress and Alzheimer’s disease
2.8 Genetics of Alzheimer’s disease
2.9 Potential novel targets for Alzheimer’s disease therapy
2.10 Summary of key findings

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Data collection methods
3.4 Data analysis techniques
3.5 Ethical considerations
3.6 Validity and reliability
3.7 Limitations of the methodology
3.8 Justification of methodology

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Novel targets identified
4.3 Potential mechanisms of action
4.4 Comparison to existing treatments
4.5 Implications for future research
4.6 Limitations of the study
4.7 Recommendations for clinical practice
4.8 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Discussion of implications
5.3 Recommendations for future research
5.4 Conclusion
5.5 Contribution to the field
5.6 Personal reflections

Thesis Overview

Alzheimer’s disease is a major public health issue, with millions of people worldwide affected by this devastating neurodegenerative disorder. Despite extensive research efforts, there is still no cure for Alzheimer’s disease, and existing treatment options are limited in their effectiveness. In recent years, there has been growing interest in exploring novel targets for Alzheimer’s disease therapy, with the hope of developing more effective treatments that can slow or even reverse the progression of the disease.

This thesis will investigate novel targets for Alzheimer’s disease therapy, with a focus on identifying potential new pathways and molecules that could be targeted to treat this condition. By conducting a comprehensive literature review, exploring the pathophysiology of Alzheimer’s disease, and outlining the research methodology, this study aims to contribute to the development of more effective therapies for Alzheimer’s disease. The findings of this research will be discussed in detail, with implications for future research and clinical practice. Ultimately, this thesis aims to make a significant contribution to the field of Alzheimer’s disease research, with the hope of improving the lives of patients and their families.

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