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Introduction

Hoarding disorder is a psychiatric condition characterized by the excessive accumulation of belongings, leading to significant distress and impairment in daily functioning. Despite the increasing recognition of hoarding disorder as a distinct mental health condition, the neurobiological mechanisms underlying this disorder remain poorly understood. This thesis aims to explore the neurobiological basis of hoarding disorder, with a focus on identifying potential biomarkers and neural circuits associated with the disorder.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of hoarding disorder
2.2 Prevalence and clinical features
2.3 Cognitive and behavioral models of hoarding
2.4 Neurobiological theories of hoarding
2.5 Imaging studies on hoarding disorder
2.6 Genetic and familial studies
2.7 Neurocognitive aspects of hoarding
2.8 Comorbidity with other psychiatric disorders
2.9 Treatment approaches
2.10 Gaps in current literature

Chapter 3: Research Methodology
3.1 Research design
3.2 Participant recruitment
3.3 Data collection methods
3.4 Neuroimaging techniques
3.5 Genetic analysis
3.6 Cognitive assessments
3.7 Statistical analysis
3.8 Ethical considerations

Chapter 4: Discussion of Findings
4.1 Neurobiological markers of hoarding disorder
4.2 Neural circuits implicated in hoarding behavior
4.3 Genetic contributions to hoarding disorder
4.4 Cognitive processes underlying hoarding behavior
4.5 Treatment implications
4.6 Future directions for research

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Implications for clinical practice
5.3 Recommendations for future research

Thesis Overview:

Hoarding disorder is a complex psychiatric condition characterized by the excessive accumulation of possessions, leading to significant distress and impairment in daily functioning. Despite the growing recognition of hoarding disorder as a distinct mental health condition, the neurobiological mechanisms underlying the disorder remain poorly understood. This thesis aims to investigate the neurobiological basis of hoarding disorder, with a focus on identifying potential biomarkers and neural circuits associated with the disorder.

The literature review will provide an overview of hoarding disorder, including its prevalence, clinical features, cognitive and behavioral models, and treatment approaches. The review will also examine current research on the neurobiological theories of hoarding, imaging studies, genetic and familial studies, neurocognitive aspects, and comorbidity with other psychiatric disorders. The chapter will conclude by identifying gaps in the current literature that the present study aims to address.

The research methodology chapter will outline the study design, participant recruitment, data collection methods, neuroimaging techniques, genetic analysis, cognitive assessments, statistical analysis, and ethical considerations. The discussion of findings chapter will present the results of the study, including neurobiological markers of hoarding disorder, neural circuits implicated in hoarding behavior, genetic contributions, cognitive processes, treatment implications, and future research directions.

The conclusion and summary chapter will provide a summary of key findings, implications for clinical practice, and recommendations for future research. Overall, this thesis aims to contribute to our understanding of the neurobiology of hoarding disorder and inform the development of more effective treatments for individuals struggling with this challenging condition.

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