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Introduction

Drug repositioning, also known as drug repurposing, is the process of discovering new uses for existing drugs that are outside the scope of their original medical indications. This approach has gained significant attention in recent years as a cost-effective and time-efficient strategy for drug development. In the context of infectious diseases, drug repositioning offers a promising avenue for identifying novel treatments, particularly in light of the growing threat of antimicrobial resistance.

Background of Study

Infectious diseases continue to be a major global health concern, causing significant morbidity and mortality worldwide. Traditional drug discovery methods have struggled to keep pace with the emergence of new infectious agents and the evolving resistance of existing pathogens to current treatments. As a result, there is an urgent need for innovative approaches to identify effective therapies for infectious diseases.

Problem Statement

The limited pipeline of new antibiotics and antiviral drugs, coupled with the high costs and long timelines associated with traditional drug development, present significant challenges in the fight against infectious diseases. Drug repositioning offers a potential solution to these challenges by repurposing existing drugs with known safety profiles and mechanisms of action for the treatment of infectious diseases.

Objective of Study

The primary objective of this thesis is to explore the potential of drug repositioning as a strategy for identifying new treatments for infectious diseases. Specifically, this study aims to investigate the feasibility and efficacy of repurposing existing drugs for the treatment of a range of infectious diseases, including bacterial, viral, and parasitic infections.

Limitation of Study

It is important to note that drug repositioning is not without its limitations. While this approach offers a cost-effective and time-efficient strategy for drug development, there are challenges related to intellectual property rights, regulatory requirements, and clinical trial design that may impact the successful implementation of drug repositioning strategies for infectious diseases.

Scope of Study

This study will focus on the exploration of drug repositioning for infectious diseases, with a specific emphasis on bacterial, viral, and parasitic infections. The research will involve a comprehensive review of the literature, as well as the development and implementation of a research methodology to investigate the potential of repurposed drugs as treatments for infectious diseases.

Significance of Study

The findings of this study have the potential to significantly impact the field of infectious disease research and drug development. By identifying novel uses for existing drugs, this research may lead to the discovery of new treatments for infectious diseases that are urgently needed to combat the global threat of antimicrobial resistance.

Structure of the Thesis

Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Drug Repositioning
2.2 Infectious Diseases
2.3 Traditional Drug Discovery Methods
2.4 Challenges in Infectious Disease Treatment
2.5 Drug Repositioning Strategies
2.6 Case Studies in Drug Repositioning for Infectious Diseases
2.7 Regulatory Considerations
2.8 Clinical Trial Design
2.9 Intellectual Property Rights
2.10 Future Directions in Drug Repositioning for Infectious Diseases

Chapter 3: Research Methodology
3.1 Research Design
3.2 Sampling Strategy
3.3 Data Collection Methods
3.4 Data Analysis Techniques
3.5 Ethical Considerations
3.6 Pilot Study
3.7 Study Timeline
3.8 Budget Allocation

Chapter 4: Discussion of Findings
4.1 Overview of Findings
4.2 Analysis of Data
4.3 Interpretation of Results
4.4 Comparison with Existing Literature
4.5 Implications for Practice
4.6 Recommendations for Future Research
4.7 Limitations of the Study

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Conclusion
5.3 Contributions to the Field
5.4 Implications for Policy and Practice
5.5 Recommendations for Further Research
5.6 Conclusion

Thesis Overview on Drug Repositioning for Infectious Diseases

Drug repositioning, also known as drug repurposing, is a strategy that involves identifying new uses for existing drugs that are outside their originally intended medical indications. This approach has gained prominence in recent years as a promising method for accelerating drug discovery and development processes, particularly in the context of infectious diseases. The rising threat of antimicrobial resistance and the limited pipeline of new antibiotics and antiviral drugs have underscored the urgent need for innovative strategies to combat infectious diseases.

This thesis aims to explore the potential of drug repositioning as a strategy for identifying new treatments for infectious diseases, focusing on bacterial, viral, and parasitic infections. The study will involve a comprehensive literature review, as well as the development and implementation of a research methodology to investigate the feasibility and efficacy of repurposed drugs in the treatment of infectious diseases. By identifying novel uses for existing drugs, this research has the potential to significantly impact the field of infectious disease research and drug development.

Overall, this thesis seeks to contribute to the growing body of knowledge on drug repositioning for infectious diseases, with the ultimate goal of advancing the development of new treatments to combat the global threat of antimicrobial resistance.

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