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Introduction:

Fasting is a common practice in many cultures and religions for various reasons including spiritual, health, and weight loss benefits. It involves abstaining from food and/or drink for a specified period of time. However, the impact of fasting on drug pharmacokinetics, the study of how drugs are absorbed, distributed, metabolized, and excreted by the body, is not well understood.

This thesis aims to explore the influence of fasting on drug pharmacokinetics and provide valuable insights into how fasting may affect the efficacy and safety of drug therapy. Understanding these interactions is crucial for healthcare professionals to optimize drug dosing regimens for patients who are fasting for religious, cultural, or medical reasons.

Table of Contents:

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Introduction to fasting
2.2 Physiological changes during fasting
2.3 Drug absorption during fasting
2.4 Drug distribution during fasting
2.5 Drug metabolism during fasting
2.6 Drug excretion during fasting
2.7 Case studies on fasting and drug pharmacokinetics
2.8 Clinical implications of fasting on drug therapy
2.9 Challenges in studying fasting and drug pharmacokinetics
2.10 Summary of key findings in the literature review

Chapter 3: Research Methodology
3.1 Research design
3.2 Sampling and recruitment
3.3 Data collection methods
3.4 Data analysis techniques
3.5 Ethical considerations
3.6 Pilot study
3.7 Data validation
3.8 Statistical analysis
3.9 Limitations of the research methodology

Chapter 4: Discussion of Findings
4.1 Overview of study findings
4.2 Impact of fasting on drug absorption
4.3 Impact of fasting on drug distribution
4.4 Impact of fasting on drug metabolism
4.5 Impact of fasting on drug excretion
4.6 Comparison with existing literature
4.7 Implications for clinical practice
4.8 Recommendations for future research

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Conclusion
5.3 Contributions to the field
5.4 Implications for healthcare professionals
5.5 Recommendations for further research

This thesis will provide a comprehensive overview of the impact of fasting on drug pharmacokinetics, shedding light on this understudied area and offering valuable insights for healthcare professionals and researchers.

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