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Introduction

Cardiovascular diseases (CVDs) remain a leading cause of death worldwide, representing a significant healthcare burden. Traditional drug development for CVDs is a lengthy and costly process, often leading to high failure rates in clinical trials. Drug repurposing, the process of identifying new uses for existing drugs, has emerged as a promising strategy to accelerate the discovery of safe and effective treatments for CVDs.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of cardiovascular diseases
2.2 Current treatments for CVDs
2.3 Drug repurposing in the pharmaceutical industry
2.4 Success stories of drug repurposing for CVDs
2.5 Challenges and limitations of drug repurposing
2.6 Computational approaches in drug repurposing
2.7 Regulatory considerations in drug repurposing
2.8 Ethical considerations in drug repurposing
2.9 Future directions in drug repurposing for CVDs
2.10 Conclusion

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection and analysis methods
3.3 Selection of candidate drugs for repurposing
3.4 In vitro and in vivo validation studies
3.5 Clinical trial design
3.6 Statistical analysis
3.7 Ethical considerations
3.8 Timeline and budget

Chapter 4: Discussion of Findings
4.1 Identification of potential candidate drugs for repurposing
4.2 In vitro and in vivo validation results
4.3 Clinical trial outcomes
4.4 Comparison with existing treatments
4.5 Safety and efficacy of repurposed drugs
4.6 Mechanisms of action
4.7 Future directions
4.8 Implications for clinical practice

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Contribution to the field
5.3 Limitations and future research directions
5.4 Conclusion

Thesis Overview on Drug Repurposing for Cardiovascular Diseases:

Cardiovascular diseases (CVDs) are a major public health concern worldwide, contributing significantly to morbidity and mortality. Traditional drug development processes for CVDs are time-consuming, expensive, and often result in high failure rates during clinical trials. Drug repurposing, also known as drug repositioning, offers a promising alternative approach to identify new therapeutic uses for existing drugs.

This thesis aims to explore the potential of drug repurposing in the treatment of CVDs. The introduction provides a comprehensive overview of the background, problem statement, objectives, limitations, scope, significance, and structure of the thesis. In the literature review, current treatments for CVDs are discussed, along with the concept of drug repurposing in the pharmaceutical industry. Success stories, challenges, computational approaches, regulatory issues, and ethical considerations in drug repurposing for CVDs are also examined.

The research methodology chapter outlines the design, data collection, drug selection, validation studies, clinical trial design, analysis methods, ethical considerations, timeline, and budget for the study. The discussion of findings chapter presents the identification of potential candidate drugs for repurposing, validation results, clinical trial outcomes, comparisons with existing treatments, safety and efficacy evaluations, mechanisms of action, and future directions.

In the conclusion and summary chapter, the key findings are summarized, the contributions to the field are highlighted, limitations and future research directions are discussed, and a conclusion is drawn. The thesis aims to provide valuable insights into the potential of drug repurposing for the treatment of CVDs and its implications for clinical practice.

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