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Introduction:
Clostridium difficile infection (CDI) is a leading cause of healthcare-associated infections worldwide, particularly in long-term care facilities. This thesis aims to evaluate the effectiveness of nurse-led interventions in reducing hospital-acquired CDI in long-term care facilities. By examining the current literature and implementing a rigorous research methodology, this study seeks to provide insights into the role of nurses in preventing and managing CDI in these settings.

Chapter One: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter Two: Literature Review
– Overview of Clostridium difficile infection
– Prevalence and impact of CDI in long-term care facilities
– Nurse-led interventions in infection prevention and control
– Current strategies for CDI prevention
– Role of hand hygiene in CDI prevention
– Antibiotic stewardship programs in long-term care facilities
– Education and training for healthcare workers
– Surveillance and monitoring of CDI rates
– Effectiveness of probiotics in CDI prevention
– Challenges and gaps in the literature

Chapter Three: Research Methodology
– Research design
– Study population and sampling method
– Data collection tools and procedures
– Variables and measures
– Data analysis plan
– Ethical considerations
– Validity and reliability
– Limitations of the study

Chapter Four: Findings and Discussion
– Description of study sample
– Effectiveness of nurse-led interventions in reducing CDI rates
– Factors influencing the success of interventions
– Comparison of different intervention strategies
– Interpretation of results
– Implications for practice and policy
– Recommendations for future research

Chapter Five: Conclusion and Summary
– Summary of key findings
– Contribution to the literature
– Practical implications for healthcare providers
– Limitations of the study
– Suggestions for further research

Thesis Overview:
Clostridium difficile infection (CDI) is a major public health concern, especially in long-term care facilities where vulnerable populations are at increased risk. Nurse-led interventions play a crucial role in preventing and managing CDI in these settings. This thesis aims to evaluate the effectiveness of nurse-led interventions in reducing hospital-acquired CDI rates in long-term care facilities.

The literature review will provide a comprehensive overview of CDI, its prevalence in long-term care facilities, and current strategies for prevention. The research methodology will outline the study design, sampling methods, data collection tools, and analysis plan. The findings and discussion will present the results of the study, including the effectiveness of nurse-led interventions and factors influencing their success. The conclusion will summarize the key findings, implications for practice, and recommendations for future research.

By examining the effectiveness of nurse-led interventions in reducing CDI rates, this thesis aims to contribute to the body of knowledge on infection prevention and control in long-term care facilities. It is hoped that the findings will inform healthcare providers, policymakers, and researchers on the best practices for preventing and managing CDI in these settings.

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